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Diffuse Large B-cell Lymphoma

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Centroblastic variant of diffuse large B-cell lymphomas (shown here) is composed of cells that resemble their normal counterparts in a reactive germinal center. There is an admixture of cleaved and non-cleaved cells of medium to large size. The nuclei may be small, irregular and angulated OR oval/circular with multiple small nucleoli. Cytoplasm is scant and numerous mitotic figures and apoptotic cells are present.

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