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Classical Hodgkin Lymphoma : Nodular Sclerosis (Reed-Sternberg Cell)

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Classic Reed-Sternberg cell is 20 to 50 microns in size, with acidophilic or amphophilic cytoplasm, large bilobed or multilobed nucleus with vesicular or coarse chromatin. A large, round, eosinophilic central nucleolus is always present.

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