Facebook Icon Twitter icon Instagram icon Feedback

Castleman's Disease : Plasma Cell Type

prev slide 19 of 24 next
No Image


Multicentric or Systemic form of Castlemanís disease is usually of plasma cell type which shows diffuse plasma cell proliferation in the interfollicular region. The image shows a small follicle in the center with eosinophilic deposits of fibrin and immune complexes. Hyaline-vascular changes are absent. Plasma cell type of Castlemanís disease is often symptomatic and is accompanied by fever, anemia, elevated erythrocyte sedimentation rate, hypergammaglobulinemia, and hypoalbuminemia. In contrast, hyaline-vascular type is often asymptomatic.

prev slide 19 of 24 next