Apocrine CA : In-situ & Invasive
Apocrine DCIS, solid pattern, surrounded by invasive apocrine carcinoma. The tumor cells have abundant eosinophilic granular cytoplasm. Many cells show cytoplasmic vacuoles or clearing.
It must be remembered that apocrine morphology may be focally present in a variety of breast carcinomas, including ductal, lobular, mucinous, tubular, medullary and others. The term "apocrine carcinoma" is reserved for cases where majority of the tumor cells have apocrine morphology.