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Liver Cell Adenoma

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Compared to Hepatocellular Carcinoma, LCA has a relatively uniform cell population resembling normal liver, with cell plates 1-3 layers thick, an intact reticulin framework, and no mitotic activity. By definition, LCA lacks portal zones: the presence of bile ductules excludes this diagnosis. “Naked arterioles,” which lack accompanying bile ducts and are surrounded by only a thin rim of connective tissue, are characteristic of LCA.

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