Follow us:        
11,415 Images : Last Website Update : Dec 2, 2021

Melanosis coli

prev
slide 4 of 8
next
No Image
Colon_MelanosisColi1.jpg

Close

Comments:
Biopsy from an affected area of colon with melanosis coli showing sheets and clusters of macrophages containing the brownish-yellow pigment Lipofuscin. There is no inflammation.

Melanosis coli is associated with chronic use of anthraquinone-containing laxatives such as senna and rhubarb derivatives. At endoscopy, the colorectal mucosa has dark brown-black discoloration that may be diffuse or patterened (see image 1). It is a benign reversible condition and the pigmentation disappears within months once patient stops laxative use.

prev
slide 4 of 8
next