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Rosai-Dorfman Disease of Small Bowel

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SmallBowel_RosaiDorfmanDz4.jpg

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A hallmark of Rosai-Dorfman disease is emperipolesis, wherein lymphocytes are contained within the characteristic histiocytes. Several such histiocytes can be seen in this image. The lymphocytes are passing through the histiocytes and are not being degraded.

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