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Gastrointestinal Stromal Tumor - Stomach

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An ulcerated GIST originating in the muscle layer. The tumor was positive for CD117 (c-kit), CD34, and SMA (focally). It was negative for S-100 protein, ruling out a schwannoma. A more recently described immunostain, DOG-1, is considered quite specific for GIST. Image Copyright: pathorama.ch.

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