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GIST : Epithelioid

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Stomach_GIST_Epithelioid1.jpg

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This epithelioid GIST displays more plump, rounded cells with an increased nuclear:cytoplasmic ratio compared to the tumor in the previous image. This feature is suggestive of a more aggressive behavior, but this is most reliably determined based on the tumor size and mitotic rate (with > 5 mitoses/high power field being a poor prognostic indicator).

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