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Coccidioidomycosis - Spleen

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Higher magnification shows granulomas with multiple intact thick-walled, non-budding spherules 20 to 60 m in diameter within giant cells. Coccidioidomycosis is endemic in Southwest and western United States. Primay infection is asymptomatic in almost 90% of individuals. Some may develop fever, cough, pleuritis, lung lesions and skin lesions (San Joaquin Valley Fever).

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