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Warthin's Tumor : Pathogenesis

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Comments:
Warthin’s tumor (WT) is believed to develop from neoplastic transformation of salivary duct epithelium that is entrapped in intra-parotid lymph nodes during embryonic development. The presence of subcapsular sinuses in some cases of WT, the occurrence of WT in periparotid lymph nodes, and the presence of B- and T-cells in the lymphoid component of WT appear to support this theory. This high power image of WT shows bi-layered oncocytic epithelium and the stroma composed of dense lymphocytic infiltrate with prominent germinal center formation.

slide 79 of 110