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Nodular Melanoma

slide 58 of 83

Comments:
Nodular melanomas (NM) share many histologic features with superficial spreading melanoma. However, NM are sharply circumscribed and show a vertical (invasive) growth pattern (as seen here). They are not preceded by a radial growth phase. The intraepidermal atypical melanocytes are not seen beyond three epidermal ridges on either side of the tumor nodule i.e. the epidermal component does not extend laterally in relationship to the dermal component creating a well-defined nodule.

slide 58 of 83