Facebook Icon Twitter icon Instagram icon Feedback

Sebaceous Carcinoma

prev slide 46 of 84 next
No Image
Skin_SebaceousCA4.jpg

Close

Comments:
Higher magnification of a sebaceous carcinoma showing a haphazard mixture of basaloid germinative cells (predominant cell population) and smaller numbers of more mature-appearing sebaceous cells with clear or lightly eosinophilic cytoplasm. The basaloid cells have round or oval vesicular nuclei, prominent nucleoli and brisk mitotic activity. Comedonecrosis is often present. There may be perineural and lymphatic/vascular invasion. Poorly-differentiated cases are composed almost entirely of pleomorphic basaloid cells and have only rare foci of lipid-containing differentiated sebaceous cells. Some cases show prominent keratinization which may lead to diagnostic confusion with squamous cell carcinoma.

prev slide 46 of 84 next