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Urothelial CA - Lymphoepithelioma-like

slide 38 of 63

Comments:
At higher magnification, the tumor shows syncytial and trabecular growth patterns. The inflammatory component consists of lymphocytes, eosinophils, and a few plasma cells. Pure forms of lymphoepithelioma-like variant of urothelial carcinoma were initially thought to respond better to chemotherapy and considered to have a better prognosis. More recent studies do not fully support this view. Most cases present at advanced stages. An association with EBV has not been found to date.

slide 38 of 63