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Pilomatrixoma : Gross Pathology

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Pilomatrixoma is usually a solitary, well-circumscribed, multilobular tumor located in the dermis. It may extend into the subcutaneous fat. Compressed connective tissue elements around the tumor may form a pseudocapsule.

Mature lesions have a cheesy, yellow-white cut surface (due to keratin) with gritty consistency secondary to calcification.

Image courtesy of: Ed Uthman, MD, Houston, TX.

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