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Mantle Cell Lymphoma : Lymph Node

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HemePath_MCL14_LNode.jpg

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Mantle cell lymphoma in a cervical lymph node (higher magnification of the previous image). The tumor consists of a uniform population of small to medium sized lymphoid cells resembling centrocytes with irregular, indented or clefted nuclear contours. The cells have condensed nuclear chromatin, inconspicuous nucleoli, and a thin rim of cytoplasm. Larger transformed cells such as centroblasts, paraimmunoblasts, and prolymphocytes are absent.

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