Fatty Liver of Pregnancy
Comments:
Acute fatty liver of pregnancy is more frequently associated with first pregnancies, twin gestations, and male fetuses. It generally occurs late in the third trimester or in the immediate post-partum period. Histologic features include microvesicular steatosis and ballooning hepatocyte degeneration. Note the involvement pericentral hepatocytes (left half) with relative sparing of the periportal hepatocytes (right half).