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Gout : Histology

slide 19 of 28

Comments:
Uric acid crystals are water-soluble and are destroyed by formalin fixation. In formalin-fixed tissues, gouty tophi appear as large amorphous deposits in the dermis and subcutaneous tissues surrounded by granulomatous inflammation and foreign body giant cells.

Image courtesy of: Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

slide 19 of 28