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Alpha methylacyl CoA racemase (AMACR) in Prostate Cancer

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Comments:
AMACR is an enzyme with a role in the beta oxidation of branched-chain fatty acids and fatty acid derivatives. It has proven to be a useful marker for the diagnosis of small foci of adenocarcinoma in prostate needle biopsies (Z. Jiang et al. Am J Clin Pathol 2004; 122:275-289). The photomicrograph shows a small focus of adenocarcinoma with strong immunoreactivity for AMACR. For H&E stained section, see next image.

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