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DLBCL : Pseudocohesive Pattern

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Comments:
In most cases of diffuse large B-cell lymphoma (DLBCL), the neoplastic cells are discohesive and grow in a diffuse pattern. Sometimes the tumor cells form aggregates, nests, or islands separated by fibrous stroma, creating a resemblance to carcinoma. With a pseudocohesive appearance such as that seen in this DLBCL, one should exclude metastatic melanoma, carcinoma or germ cell tumor by doing an appropriate panel of immunohistochemical markers.

slide 10 of 88