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Mantle Cell Lymphoma

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Nodal involvement by mantle cell lymphoma can show three possible architectural patterns - mantle zone, nodular, or diffuse. This case had a predominant nodular pattern. Transitional areas between different patterns may be seen. When nodularity is prominent, it may be confused with follicular lymphoma at low magnification. Image courtesy of: Genevieve Crane, MD, PhD, Johns Hopkins Hospital, Baltimore, Maryland, USA.

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