Gastrointestinal tract is involved in 10% to 25% of cases of mantle cell lymphoma. It may take the form of multiple small polyps in small and large bowel (lymphomatoid polyposis), a single bulky tumor nodule, superficial ulcers, or just diffuse thickening of the mucosa. Besides MCL, lymphomatoid polyposis type presentation can also be caused by follicular lymphomas and marginal zone lymphomas of the MALT type. The presenting symptoms include abdominal pain, diarrhea, and melena. The photographs shows mantle cell lymphoma of the ileo-cecal junction in a 70 y/o male. Image copyright: pathorama.ch.