Mantle Cell Lymphoma : Spleen
A classic case of mantle cell lymphoma consists of a uniform population of small to medium sized lymphoid cells resembling centrocytes with irregular, indented or clefted nuclear contours. The cells have condensed nuclear chromatin, inconspicuous nucleoli, and a thin rim of cytoplasm. Larger cells such as centroblasts and immunoblasts are absent. Histiocytes with pink cytoplasm are scattered in the background.