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Pheochromocytoma

slide 29 of 60

Comments:
This case shows nests and clusters of tumor cells with abundant dense amphophilic cytoplasm separated by a highly vascular stroma. The cytoplasm is granular due to the presence of membrane-bound, electron-dense secretory granules containing catecholamines. The nuclei are round or oval with one or more prominent nucleoli. Some of nuclei show degenerative atypia consisting of smudged chromatin.

slide 29 of 60