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Clear Cell Sarcoma of Kidney

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In its classic form, the clear cell sarcoma of kidney (CCSK) consists of nests, cords, and sheets of somewhat monomorphic tumor cells with scant cytoplasm and a high nucleus:cytoplasmic ratio. The tumor has a prominent network of delicate vasculature (chicken wire pattern similar to that seen in myxoid liposarcoma). The term "Clear Cell" is a misnomer since the clear cell appearance is caused not by the cytoplasm but is the result of loose spacing of tumor cells with intervening clear mucoid matrix.

slide 24 of 35