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Extramedullary Hematopoiesis in a Lymph Node

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High power view of extramedullary hematopoiesis in a lymph node showing megakaryocytes within a background of maturing granulocytic elements. The presence of megakaryocytes may create confusion with Hodgkin's disease. Immunostain for CD61 (megakaryocytic marker; see next image) can help sort out the diagnosis. Image courtesy of Dr. Michael Spears, USA. Used with permission.

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