Striving to be the most comprehensive online resource for high-quality pathology images

 

Adult Granulosa Cell Tumor : Cytologic Features

prev  
slide 41 of 104
next
No Image
Ovary_AdultGCT_Nuclei10.jpg

Close

Comments:
Cytologic Features of Adult Granulosa Cell Tumor (GCT) of the Ovary: The tumor cells have scant cytoplasm and pale-staining, angular to oval nuclei with longitudinal grooves or folds resulting in coffee-bean appearance. Nuclear grooves are not unique to adult GCT. They may be seen in other ovarian tumors such as Brenner tumor, steroid cell tumors, cellular fibromas, and transitional cell carcinoma.

The nuclei are arranged haphazardly with respect to one another. Mitotic activity is low and does not exceed 1-2 mitoses/10 HPF. If there is increased mitotic activity, especially if abnormal forms are present, the possibility of carcinoma should be considered. This image shows several Call-Exner bodies.

prev
slide 41 of 104
next