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Benign Brenner Tumor

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Benign Brenner tumors are composed of cells resembling mature transitional epithelium (urothelium) arranged in sharply defined solid clusters, nests and trabeculae within a dense fibromatous stroma.

The transitional cells have pale eosinophilic or clear cytoplasm, uniform round or ovoid nuclei which may have grooves, fine chromatin, and punctate nucleoli. There is no cytologic atypia and mitotic activity is not increased.

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