Higher magnification of the previous image showing stellate cells in abundant myxoid matrix. Hemosiderin-laden macrophages and delicate blood vessels are also present. The clinical manifestations of myxomas depend upon their location. Left-sided tumors can cause manifestations of mitral stenosis or insufficiency and multiple emboli in systemic circulation leading to cerebral or myocardial infarcts. Right-sided tumors may cause syncope, dyspnea, and prominence of neck veins. Some cases are associated with polycythemia. The diagnosis is established with two-dimensional echocardiography.