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Dermatofibro-sarcoma Protuberans

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SoftTissue_Fibrohistiocytic_DFSP4_cropped.jpg

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High power view showing a mitotic figure just below the center of the image. Conventional DFSP has <5 mitoses per 10 HPF. With regards to immunohistochemistry, DFSP's are CD34+ve. This feature is useful in distinguishing them from benign fibrous histiocytomas which are usually CD34 negative.

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