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Diffuse Idiopathic Neuroendocrine Cell Hyperplasia

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Lung_DIPNECH3.jpg

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Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) refers to proliferation of pulmonary neuroendocrine cells within the walls of airways. The image shows one such focus.

Differential diagnosis: Reactive proliferation of pulmonary neuroendocrine cells vs DIPNECH: Proliferation of pulmonary neuroendocrine cells may be seen in the setting of inflammatory or fibrotic lesions in the lungs. These conditions can be distinguished from DIPNECH by the presence of the underlying condition and the absence of carcinoid tumors.

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