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Hodgkin Lymphoma - Gross

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78 y/o man with hepatosplenomegaly. Splenectomy specimen showed scattered gray-white nodules. The tumor cells were positive for CD15, CD30, CD20 (partial) and negative for CD45. Spleen is the most common extranodal site of involvement in Hodgkin lymphoma. Primary Hodgkin lymphoma of spleen is rare.

slide 1 of 4