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Fibrous Dysplasia : Mazabraud Syndrome

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Mazabraud syndrome consists of fibrous dysplasia (usually polyostotic form) with multiple intramuscular myxomas affecting the same anatomical region.

Case history: 40 y/o male with hip pain. No history of trauma. The distal femur and tibia are grossly abnormal and show changes of fibrous dysplasia consisting of diffuse areas of ground-glass opacity, soap-bubbly trabeculation, endosteal irregularity, cortical thinning and moderate osseous expansion. The epiphyses are spared and there is no periosteal reaction. MRI scan showed 3 distinct intramuscular myxomas in the vastus medialis muscle near the affected areas of femur. Same case as the previous three images.

Case courtesy of Dr Matt Skalski, Radiopaedia.org. From the case rID: 37966

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