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Chondroblastic Osteosarcoma

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Bone_Osteosarcoma7_Chondroblastic_BaseofSkull.jpg

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In chondroblastic osteosarcomas, the cartilaginous areas are often arranged in lobules. The center of the lobules are less cellular than the periphery (shown on the lower left). Islands of osteoid matrix are seen within the cartilage. The periphery of the cartilaginous areas show condensation and spindling of the tumor cells.

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