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Seminoma : Syncytiotrophoblastic Cells

slide 59 of 114

Comments:
A huge syncytiotrophoblastic giant cell with hundreds of nuclei is seen in this image. It is surrounded by typical seminoma cells and lymphoid infiltrate. Syncytiotrophoblastic giant cells are positive for beta-hCG immunostain. There is no evidence that classic seminomas containing syncytiotrophoblastic elements behave any more aggressively than tumors lacking them.

slide 59 of 114