Orchiectomy was performed in this middle-aged male who presented with several months' history of chronic testicular pain not responding to antibiotic therapy. Testicular ultrasound was suggestive of epididymo-orchitis but neoplasm could not be definitively ruled out. Sections showed destruction of native architecture of both testis and epididymis. Findings included a mixed inflammatory infiltrate, seminiferous tubule destruction, abscess formation (corresponding to the yellow foci in testis) and fibrosis. The inflammatory process extends into paratesticular soft tissues which are greatly expanded as seen in this gross specimen photograph.