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HMWCK in Post-atrophic Hyperplasia

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Prostate_Immuno8B_HMWCK_PAH.jpg

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The distinction of post-atrophic hyperplasia from adenocarcinoma usually does not pose a diagnostic challenge. In rare cases with somewhat overlapping features, immunostaining with basal cell-specific markers can help. The image shows strong staining with high molecular weight cytokeratin and p63 in the entire focus. Note the lobular arrangement of the glands.

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