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Hepatoblastoma - Fetal pattern

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Comments:
At high power, fetal epithelial-type hepatoblastoma may show mild cytologic atypia, with enlarged nuclei and prominent nucleoli, as seen in reactive hepatocytes and well-differentiated hepatocellular carcinomas. Some tumor cells appear lighter due to cytoplasmic lipid and glycogen, while others have eosinophilic cytoplasm, resembling non-neoplastic adult hepatocytes.

slide 7 of 64