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Prostate Cancer : Signet Ring-Cell Type

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Prostate_CaP_Variants_SignetRing2_R.jpg

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The signet-ring cells are arranged in sheets and clusters in this image. The nuclei are deeply hyperchromatic. Nucleoli are not visible. In most cases, the cytoplasmic vacuoles creating a signet-ring appearance are either empty or contain lipid. Intracellular mucin is found only in rare cases in small quantities.

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