This colectomy specimen is from a 40 y/o female who presented with abdominal pain, vomiting, and constipation. Imaging studies revealed a circumferential growth in the descending colon 45 cm proximal to the anal verge. The specimen shows a 5 cm fleshy, gelatinous tumor causing luminal stenosis. Microscopically, it was composed of mucus-secreting invasive adenocarcinoma. Lymphovascular invasion and metastases to pericolic lymph nodes were also found. Case courtesy of: Dr. Sanjay D. Deshmukh, Professor of Pathology, Smt. Kashibai Navale Medical College, Pune, India.