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Prostatic xanthoma

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Comments:
At higher magnification, one can appreciate small, hyperchromatic nuclei with inconspicuous nucleoli, abundant foamy cytoplasm, and pigment. There is no cytologic atypia or increased mitotic activity. Foamy gland variant of prostatic adenocarcinoma may also demonstrate small hyperchromatic nuclei and clear or foamy cytoplasm; however, usually, there is glandular differentiation nearby which may point to the correct diagnosis.

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