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Gastric Adenocarcinoma, Diffuse Type (Linitis Plastica; Signet Ring Cell Carcinoma)

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Comments:
Single tumor cells are present in the bands of fibrosis between muscle bundles. Prominent desmoplastic response and muscle hypertrophy thickens the stomach wall with flattening of the rugal folds in cases of signet ring cell carcinoma.

slide 16 of 35