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Gastric Adenocarcinoma, Diffuse Type (Linitis Plastica; Signet Ring Cell Carcinoma)

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Comments:
The tumor cells have large intracytoplasmic vacuoles that push the nucleus to the periphery creating a signet ring appearance. Diffuse subtype of gastric carcinoma tends to involve younger patients more frequently than the intestinal subtype.

slide 13 of 35