 |
|
|
1:
Mature Teratoma: Cartilage
|
|
Comments: Teratoma is the 2nd most common testicular germ cell tumor in children (after Yolk Sac Tumor). Mature teratomas display a variety of somatic-type tissues, including cartilage (shown here), muscle (smooth & skeletal), intestinal-type glands (seen in images 3 & 4), and squamous epithelium.
|
|
|
|
|
|
2:
Mature Teratoma: Skin
|
|
Comments: Islands of squamous epithelium in a case of mature teratoma in an adult male.
|
|
|
|
|
|
|
|
4:
Mature Teratoma: Intestinal-type glands
|
|
Comments: The intestinal-type glands show nuclear hyperchromasia; however, significant atypia is not present. It is not uncommon to find cytologic atypia in such tissues in post-pubertal males. Atypia does not appear to have any progrostic relevance from the available evidence.
|
|
|
|
|
|
|
|
6:
Immature Teratoma: Blastema
|
|
Comments: Islands of small hyperchromatic cells (blastema) are surrounded by myxomatous stroma and primitive glands.
|
|
|
|
|
|
|
|
8:
Testis : Primary Carcinoid
|
|
Comments: Primary testicular carcinoid is considered to be a monodermal form of teratoma. About 25% of testicular carcinoids contain other teratomatous elements. Metastases from elsewhere must be ruled out. In this image, carcinoid is on the lower right; uninvolved testicular parenchyma (seminiferous tubules) are on the upper left.
|
|
|
|
|
|
9:
Testis : Primary Carcinoid
|
|
Comments: The tumor has typical morphology seen in other locations. Nests and clusters of cells are separated by fibrous stroma. They have eosinophilic cytoplasm and round nuclei with “salt and pepper” chromatin. Primary testicular carcinoid has good prognosis with metastasis occurring in only about 12% of cases. Cancer 1993 Sept; 72(5):1726-32.
|
|
|
